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- W2349444009 abstract "Objective To research the functions of survivin,Fas and bcl-2 in bladder transitional cell carcinoma(TCC) to provide non-invasive,sensitive indicators for early diagnosis of TCC.Methods The expressions of survivins of blood and urine were determined respectively by RT-PCR in 68 patients with TCC,30 patients with other diseases of urinary system and 30 cases of normal group.Fas and bcl-2 expressions were determined by Flow Cytometry.Results Survivin and bcl-2 expressions of TCC group were significantly higher than those in the control group and the normal group(P0.01).The expressions of Fas of TCC group were significantly lower than those in the control group and the normal group(P0.01).The survivin was correlated positively with bcl-2(r=0.3126,P0.05) and negatively with Fas(r=-0.3567,P0.05).ConclusionThe positive rate can be improved with simultaneous detection of the expressions of Survivin,Fas and bcl-2.These Indicators might be the sensitive indicator for early diagnosis of TCC,which provides a simple non-invasive detection methods for new and recurrence of TCC." @default.
- W2349444009 created "2016-06-24" @default.
- W2349444009 creator A5009086157 @default.
- W2349444009 date "2010-01-01" @default.
- W2349444009 modified "2023-09-28" @default.
- W2349444009 title "SIGNIFICANCE OF SURVIVIN FAS AND BCL-2 EXPRESSIONS IN THE PERIPHERAL BLOOD OF PATIENTS WITH TCC" @default.
- W2349444009 hasPublicationYear "2010" @default.
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