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- W2349507992 abstract "Objective To evaluate the effects of low-dose ketamine on the efficacy of intravenous PCA(PCIA) with fentanil after surgery in burn patients with respiratory paths.Methods Fifty ASAⅠorⅡburn patients with respiratory paths aged 20~45 yr undergoing elective surgery under general anesthesia were randomized into 2 groups(n=25 each) according to the composition of solution: group I fentanil 15μg/kg;group Ⅱ fentanil 15μg/kg + ketamine 100mg.8mg of ondansetron was added to each recipe,and then diluted into 100mL with normal saline.The PCIA setting was as follows: background infusion 2mL/h,bolus dose 0.5 mL,lockout interval 15 min.The PCIA was given at the end of operation.Blood pressure(BP),respiration rate(HR) and pulse O2 saturation(SpO2) were monitored within 48 h after operation.Analgesia scores were record.Complications incluing nausea and vomiting and pruritus and uroschesis and hallucination and respiratory depression were recorded.Results BP,HR and SpO2 showed no significant change between the two groups.Compared with group I,Analgesia scores wre significantly decreased in group Ⅱ(P0.05).The incidence of nausea,vomiting,d pruritus and uroschesis in group Ⅱ was significantly lower than those in Group I(P0.05).There was no hallucination and respiratory depression between the two groups.Conclusion Low-dose ketamine can improve the efficacy of PCIA with fentanil after surgery in burn patients with respiratory paths with lower adverse effects." @default.
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- W2349507992 date "2011-01-01" @default.
- W2349507992 modified "2023-09-22" @default.
- W2349507992 title "Effects of Low-dose Ketamine on Efficacy of PCIA with Fentanil after Surgery In Burn Patients with Respiratory Paths" @default.
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