Matches in SemOpenAlex for { <https://semopenalex.org/work/W2349511670> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2349511670 abstract "Objective To study urinary neutrophil gelatinase-associated lipocalin( u NGAL) in the patients with systemic lupus erythematosus( SLE) and analyze its association with disease activity and pathology classification for lupus nephritis( LN). Methods The serum and urine samples of 104 SLE patients and 60 controls were collected. SLE patients were further divided into lupus nephritis( LN,n = 63) and non-nephritis SLE( n = 41). The controls consisted of 30 patients with non-SLE autoimmune diseases and 30 healthy volunteers. The concentrations of s NGAL and u NGAL were measured by latex-enhanced turbidimetric immunoassay method.Results u NGAL levels in the patients with LN were significantly higher than those without LN( P 0. 01) but the difference of s NGAL levels between the two groups did not showed statistical significance. In the patients with LN,u NGAL levels in active LN were higher than those in inactive LN( 0. 8 ± 0. 4 ng / mg Cr vs 0. 5 ± 0. 3 ng / mg Cr,P 0. 01). u NGAL levels positively correlated with the renal score of the Systemic Lupus Erythmatosus Disease Activity Index( SLEDAI)( r = 0. 364,P 0. 01). The ROC curve of u NGAL showed the level of u NGAL at cut-off point( 0. 585 ng / mg Cr) exhibited high sensitivity and specificity( 70. 73% and 77. 27%respectively)( P 0. 01). The area under ROC curve was 0. 756. The comparison of u NGAL levels among the groups with different WHO classes of LN yielded no significant difference( P 0. 05),though the patients with LN class Ⅲ and Ⅳ had elevated u NGAL.Conclusion u NGAL levels elevated promptly in SLE patients with renal involvement. u NGAL represents a novel sensitive biomarker for predicting disease activity in LN. There was no significant difference in u NGAL levels among different types of LN. u NGAL can not be used to monitor the development of the patients with proliferative renal disease." @default.
- W2349511670 created "2016-06-24" @default.
- W2349511670 creator A5012954831 @default.
- W2349511670 date "2015-01-01" @default.
- W2349511670 modified "2023-09-25" @default.
- W2349511670 title "Neutrophil gelatinase-associated lipocal in urine: a novel biomarker of disease activity and pathology classification for lupus nephritis" @default.
- W2349511670 hasPublicationYear "2015" @default.
- W2349511670 type Work @default.
- W2349511670 sameAs 2349511670 @default.
- W2349511670 citedByCount "0" @default.
- W2349511670 crossrefType "journal-article" @default.
- W2349511670 hasAuthorship W2349511670A5012954831 @default.
- W2349511670 hasConcept C126322002 @default.
- W2349511670 hasConcept C159654299 @default.
- W2349511670 hasConcept C185592680 @default.
- W2349511670 hasConcept C20299238 @default.
- W2349511670 hasConcept C203014093 @default.
- W2349511670 hasConcept C2775915377 @default.
- W2349511670 hasConcept C2776912625 @default.
- W2349511670 hasConcept C2777058396 @default.
- W2349511670 hasConcept C2779134260 @default.
- W2349511670 hasConcept C2779912601 @default.
- W2349511670 hasConcept C2780026642 @default.
- W2349511670 hasConcept C2781197716 @default.
- W2349511670 hasConcept C55493867 @default.
- W2349511670 hasConcept C71924100 @default.
- W2349511670 hasConcept C76318530 @default.
- W2349511670 hasConcept C77411442 @default.
- W2349511670 hasConcept C90924648 @default.
- W2349511670 hasConceptScore W2349511670C126322002 @default.
- W2349511670 hasConceptScore W2349511670C159654299 @default.
- W2349511670 hasConceptScore W2349511670C185592680 @default.
- W2349511670 hasConceptScore W2349511670C20299238 @default.
- W2349511670 hasConceptScore W2349511670C203014093 @default.
- W2349511670 hasConceptScore W2349511670C2775915377 @default.
- W2349511670 hasConceptScore W2349511670C2776912625 @default.
- W2349511670 hasConceptScore W2349511670C2777058396 @default.
- W2349511670 hasConceptScore W2349511670C2779134260 @default.
- W2349511670 hasConceptScore W2349511670C2779912601 @default.
- W2349511670 hasConceptScore W2349511670C2780026642 @default.
- W2349511670 hasConceptScore W2349511670C2781197716 @default.
- W2349511670 hasConceptScore W2349511670C55493867 @default.
- W2349511670 hasConceptScore W2349511670C71924100 @default.
- W2349511670 hasConceptScore W2349511670C76318530 @default.
- W2349511670 hasConceptScore W2349511670C77411442 @default.
- W2349511670 hasConceptScore W2349511670C90924648 @default.
- W2349511670 hasLocation W23495116701 @default.
- W2349511670 hasOpenAccess W2349511670 @default.
- W2349511670 hasPrimaryLocation W23495116701 @default.
- W2349511670 hasRelatedWork W2004560219 @default.
- W2349511670 hasRelatedWork W2009800333 @default.
- W2349511670 hasRelatedWork W2059076869 @default.
- W2349511670 hasRelatedWork W2086943252 @default.
- W2349511670 hasRelatedWork W2121191867 @default.
- W2349511670 hasRelatedWork W2338273860 @default.
- W2349511670 hasRelatedWork W2552614853 @default.
- W2349511670 hasRelatedWork W2587729696 @default.
- W2349511670 hasRelatedWork W2610021441 @default.
- W2349511670 hasRelatedWork W2620463176 @default.
- W2349511670 hasRelatedWork W2775820434 @default.
- W2349511670 hasRelatedWork W2792524355 @default.
- W2349511670 hasRelatedWork W2909131457 @default.
- W2349511670 hasRelatedWork W2949600520 @default.
- W2349511670 hasRelatedWork W3029670474 @default.
- W2349511670 hasRelatedWork W3031778219 @default.
- W2349511670 hasRelatedWork W3036415944 @default.
- W2349511670 hasRelatedWork W3091608512 @default.
- W2349511670 hasRelatedWork W3099943271 @default.
- W2349511670 hasRelatedWork W3110251087 @default.
- W2349511670 isParatext "false" @default.
- W2349511670 isRetracted "false" @default.
- W2349511670 magId "2349511670" @default.
- W2349511670 workType "article" @default.