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- W2349530561 abstract "Objective: To investigate the clinical value of using probiotics in patients after liver transplantation.Methods: Fifty-five patients were randomly allocated either to probiotics treatment group or control group after receiving liver transplantation.All patients received immunosuppressant therapy after operation,while those in probiotics treatment group were additionally given bifidobacterium tetravaccine tablets for one week(siliankang,1.5 g,3 times daily).The serum levels of total bilirubin(TBIL),alanine aminotransferase(ALT),albumin(ALB) and prealbumin(PA) of the patients were measured before operation and on postoperative day(POD) 2,5 and 8,respectively.In addition,the incidences of postoperative infection and gastrointestinal adverse events of the patients were observed and recorded.Results: The serum levels of TBIL and ALT between the two groups showed no difference before operation and on POD 2(all P0.05),but TBIL and ALT level in probiotics treatment group began to decrease significantly on POD 8 and POD 5 respectively compared with control group(both P0.05).The serum levels of ALB and PA of the two groups had no obvious difference before operation and on POD 2,but both levels in probiotics treatment group were significantly higher than those of control group on POD 5 and 8(all P0.05).The incidences of infection and gastrointestinal adverse events of probiotics group and control group were 41.38% vs.17.24%(P=0.038) and 69.23% vs.42.31%)(P=0.041) respectively during the first week after operation.Conclusion: Application of probiotics can improve the nutritional status,promote liver function recovery,decrease the inflammatory response,and reduce the incidence of infection and gastrointestinal adverse reaction in patients after liver transplantation." @default.
- W2349530561 created "2016-06-24" @default.
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- W2349530561 date "2013-01-01" @default.
- W2349530561 modified "2023-09-26" @default.
- W2349530561 title "Beneficial effects of probiotics regimen in patients after liver transplantation" @default.
- W2349530561 hasPublicationYear "2013" @default.
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