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- W2349583571 abstract "Purpose Hydroxyethylpuerarin(compound N2035) is modified in structure from puerarin which was extracted from Chinese traditional medicinal plant,R.Puerariae.This study is to investigate the effect of hydroxyethylpuerarin on adrenergic receptor.MethodsThe models of isolated rabbit aortic strips and isolated hearts were used to investigate the effect of hydroxyethylpuerarin on α and β-adrenoceptors.ResultsHydroxyethylpuerarin decreased the ranges of heart-tension curves and made the frequency slow.These effects were similar to propranolol.Hydroxyethylpuerarin could not obviously inhibit the contraction of the aortic strips induced by noradrenaline.ConclusionHydroxyethylpuerarin can block β-adrenoceptor on myocardium but has no obvious effect on α-adrenoceptor on vessels." @default.
- W2349583571 created "2016-06-24" @default.
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- W2349583571 date "2006-01-01" @default.
- W2349583571 modified "2023-09-23" @default.
- W2349583571 title "The effect of hydroxyethylpuerarin on β-adrenergic receptors" @default.
- W2349583571 hasPublicationYear "2006" @default.
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