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- W2349663673 abstract "Objective The article is to investigate the effect of pravastatin on plasma level of soluble CD40 ligand (sCD40L) in acute coronary syndrome (ACS) patients. Method 38 cases of ACS patients, 32 cases of stable angina pectoris (SAP) patients and 40 cases of normal volunteer were chosen. Plasma levels of sCD40L in above patients were detected by ELISA. After the detection, ACS patients and SAP patients were given pravastatin (20 mg/d) for 8 weeks, and then, the levels of sCD40L were detected again. Result The level of sCD40L in ACS patients was higher than that in SAP and normal patients; there was no difference between SAP and normal patients. A positive correlation existed between plasma sCD40L and TC LDL-C, and negative correlation between plasma sCD40L and HDL-C. The level of sCD40L in ACS had declined since pravastatin was administrated. Conclusion Plasm level of sCD40L becoming higher in ACS patients may be related to the pathogenesis of ACS.Pravastatin can reduce plasma level of sCD40L, contributing to treatment of ACS." @default.
- W2349663673 created "2016-06-24" @default.
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- W2349663673 date "2004-01-01" @default.
- W2349663673 modified "2023-09-28" @default.
- W2349663673 title "An effect study on pravastatin on plasma level of soluble CD40 ligand in acute coronary syndrome" @default.
- W2349663673 hasPublicationYear "2004" @default.
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