Matches in SemOpenAlex for { <https://semopenalex.org/work/W2349672624> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2349672624 abstract "AIM: To explore the effect of deoxynivalenol on apoptosis and proliferation of mouse thymocytes in vivo. METHODS: Effect of deoxynivalenol at different concentrations on apoptosis and proliferation of mouse thymocytes in vivo were studied with animal experiment, electron microscopic observation, DNA agarose gel electrophoresis and flow cytometric analyses. RESULTS: FCM analysis showed that the apoptosis rates of the thymocytes in DON groups (0 5 mg/kg, 1 mg/kg, 2 mg/kg, 4 mg/kg and 8 mg/kg) were significantly higher than that in control ( P 0 01). In the concentration ranging from 0 5 mg/kg to 8 mg/kg, a significant dose-dependant response correlation could be found between apoptosis rate and DON concentration. The result of DNA agarose gel electrophoresis showed that characteristic DNA ladder was found in groups treated DON at relatively higher concentrations (8 mg/kg and 4 mg/kg). Ultrastructurally, chromatin condensation and nuclear budding phenomenon could be found in the cells treated with DON. In addition to the effects on apoptosis, 4 mg/kg and 8 mg/kg DON treatment could significantly decrease the PIs of the treated thymocytes in vivo as compared with control. CONCLUSION:DON can induce and enhance murine thymocytes apoptosis in a dose-dependant manner and inhibit the proliferation activities of the treated cells." @default.
- W2349672624 created "2016-06-24" @default.
- W2349672624 creator A5066675122 @default.
- W2349672624 date "2002-01-01" @default.
- W2349672624 modified "2023-09-25" @default.
- W2349672624 title "Effects of deoxynivalenol on apoptosis and proliferation of mouse thymocytes in vivo" @default.
- W2349672624 hasPublicationYear "2002" @default.
- W2349672624 type Work @default.
- W2349672624 sameAs 2349672624 @default.
- W2349672624 citedByCount "0" @default.
- W2349672624 crossrefType "journal-article" @default.
- W2349672624 hasAuthorship W2349672624A5066675122 @default.
- W2349672624 hasConcept C116084860 @default.
- W2349672624 hasConcept C153911025 @default.
- W2349672624 hasConcept C16685009 @default.
- W2349672624 hasConcept C185592680 @default.
- W2349672624 hasConcept C190283241 @default.
- W2349672624 hasConcept C203014093 @default.
- W2349672624 hasConcept C207001950 @default.
- W2349672624 hasConcept C2776090121 @default.
- W2349672624 hasConcept C2778271344 @default.
- W2349672624 hasConcept C2778476535 @default.
- W2349672624 hasConcept C2778954852 @default.
- W2349672624 hasConcept C54355233 @default.
- W2349672624 hasConcept C552990157 @default.
- W2349672624 hasConcept C553184892 @default.
- W2349672624 hasConcept C55493867 @default.
- W2349672624 hasConcept C71924100 @default.
- W2349672624 hasConcept C86803240 @default.
- W2349672624 hasConcept C8891405 @default.
- W2349672624 hasConceptScore W2349672624C116084860 @default.
- W2349672624 hasConceptScore W2349672624C153911025 @default.
- W2349672624 hasConceptScore W2349672624C16685009 @default.
- W2349672624 hasConceptScore W2349672624C185592680 @default.
- W2349672624 hasConceptScore W2349672624C190283241 @default.
- W2349672624 hasConceptScore W2349672624C203014093 @default.
- W2349672624 hasConceptScore W2349672624C207001950 @default.
- W2349672624 hasConceptScore W2349672624C2776090121 @default.
- W2349672624 hasConceptScore W2349672624C2778271344 @default.
- W2349672624 hasConceptScore W2349672624C2778476535 @default.
- W2349672624 hasConceptScore W2349672624C2778954852 @default.
- W2349672624 hasConceptScore W2349672624C54355233 @default.
- W2349672624 hasConceptScore W2349672624C552990157 @default.
- W2349672624 hasConceptScore W2349672624C553184892 @default.
- W2349672624 hasConceptScore W2349672624C55493867 @default.
- W2349672624 hasConceptScore W2349672624C71924100 @default.
- W2349672624 hasConceptScore W2349672624C86803240 @default.
- W2349672624 hasConceptScore W2349672624C8891405 @default.
- W2349672624 hasLocation W23496726241 @default.
- W2349672624 hasOpenAccess W2349672624 @default.
- W2349672624 hasPrimaryLocation W23496726241 @default.
- W2349672624 hasRelatedWork W2029685880 @default.
- W2349672624 hasRelatedWork W2071811576 @default.
- W2349672624 hasRelatedWork W2139499838 @default.
- W2349672624 hasRelatedWork W2267149644 @default.
- W2349672624 hasRelatedWork W2350350605 @default.
- W2349672624 hasRelatedWork W2352487517 @default.
- W2349672624 hasRelatedWork W2357546538 @default.
- W2349672624 hasRelatedWork W2364692508 @default.
- W2349672624 hasRelatedWork W2367558964 @default.
- W2349672624 hasRelatedWork W2374704121 @default.
- W2349672624 hasRelatedWork W2378928731 @default.
- W2349672624 hasRelatedWork W2381349774 @default.
- W2349672624 hasRelatedWork W2383474309 @default.
- W2349672624 hasRelatedWork W2384075892 @default.
- W2349672624 hasRelatedWork W2392224847 @default.
- W2349672624 hasRelatedWork W2410072528 @default.
- W2349672624 hasRelatedWork W2423129295 @default.
- W2349672624 hasRelatedWork W2884706282 @default.
- W2349672624 hasRelatedWork W3030141781 @default.
- W2349672624 hasRelatedWork W3032219906 @default.
- W2349672624 isParatext "false" @default.
- W2349672624 isRetracted "false" @default.
- W2349672624 magId "2349672624" @default.
- W2349672624 workType "article" @default.