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- W2349728449 abstract "Objective To explore the mechanism and effects of enteral nutrition on intestine damage induced by severe burns.Methods Wistar rats were inflicted with 30% total body surface area full thickness burns and randomly divided into three groups:namely burned and enteral nutrition(EN), burned and parenteral nutrition(PN), and normal control(C). In EN and PN group, rats were supplied with equal volume, calorie, nitrogen and other nutrients. The following indices including the activity of diamine oxidase(DAO), the level of plasma endotoxin, index of intestinal epithelial proliferation and mucus layer depth were determined.Results After burn injury, the structure of intestine was severely damaged and the activity of DAO as well as plasma endotoxin was significant increased. On the other hand, intestinal epithelial proliferation index and mucus layer depth were remarked declined. As compared with PN, EN could abate intestine injury obviously, and lessen the degree of DAO and plasma endotoxin increased as well as intestinal epithelial proliferation index and mucus layer depth decreased, though it could not reverse this trend.Conclusion After burn injury, intestine mucosa are damaged and the ability of intestine epithelial cell proliferation is significant declined.Compare with parenteral nutrition, enteral nutrition is beneficial in minimizing intestine injury, promoting intestinal mucosa reparation" @default.
- W2349728449 created "2016-06-24" @default.
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- W2349728449 date "2002-01-01" @default.
- W2349728449 modified "2023-09-27" @default.
- W2349728449 title "Experimental study of enteral nutrition minimizing intestine damage induced by severe burns" @default.
- W2349728449 hasPublicationYear "2002" @default.
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