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- W2349738596 abstract "The aim of this study was to evaluate effect of dietary nucleotides on inflammation and anti-inflammation homeostasis.Mice were administrated with nucleotide-free(NF) or nucleotide-supplemented(NT) diet,and inflammatory cytokine IL-1,IFN-γ,anti-inflammatory cytokine IL-10 and intestinal myeloperoxidase(MPO) were determined at 4th and 18th h after stimulation with CpG DNA and LPS.Production of IL-1(P0.05),IFN-γ(P0.01) and activity of MPO(P0.01) decreased,whereas production of IL-10(P0.05)increased with nucleotides supplement at 4th h after stimulation.At 18th h after stimulation,production of IL-1(P0.01),IFNγ(P0.01),IL-10(P0.05) and activity of MPO(P0.01) were lower than that at 4th h.Production of IL-1(P0.05),IFN-γ(P0.01) and activity of MPO((P0.01)) in Groups NT were still lower than that in Groups NF,and production of IL-10(P0.05) was still higher than that in Groups NF.The results indicated dietary nucleotides can depress inflammation induced by CpG DNA or LPS,maintain inflammatory and anti-inflammatory balance and protect animals from injury." @default.
- W2349738596 created "2016-06-24" @default.
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- W2349738596 date "2006-01-01" @default.
- W2349738596 modified "2023-09-26" @default.
- W2349738596 title "Effects of dietary nucleotides on inflammatory and anti-inflammatory balance" @default.
- W2349738596 hasPublicationYear "2006" @default.
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