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- W2349768011 abstract "AIM:To evaluate the efficacy and safety of flupentixol/melitracen(FM) in the treatment of poststroke depression(PSD). METHODS:One hundred and seven patients with PSD were randomly assigned into 2 groups. FM group 54 patients (M 44,F 10,age 59 a± s 9 a) were treated with FM 2-4 tab·d -1 , po ,for 6 wk. Gontrol group 53 patients (M 39,F 14,age 60 a±8 a) were treated with amitriptyline,25 50 mg, po ,tid,for 6 wk.Effects and adverse reactions were evaluated with Hamilton depression scale (HAMD),Hamilton anxiety scale (HAMA),clinical globle impression scale(CGI)and treatment emergent symptoms scale (TESS) before and after the treatment. RESULTS:Each group reached significant reduction on total scores of HAMD,HAMA and CGI ( P 0.01).The total response rate of FM and control group were 95% and 96%, respectively ( P 0.05).The adverse reactions of FM group were significantly lower than control group ( P 0.01). CONCLUSION:The FM is effective and safe for treatment of PSD." @default.
- W2349768011 created "2016-06-24" @default.
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- W2349768011 date "2000-01-01" @default.
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- W2349768011 title "Flupentixol/melitracen in treatment of poststroke depression" @default.
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