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- W2349780842 abstract "In order to investigate the effect of active constitutents of echinacea、astragalus on immunoloregulation mechanism of IBDV chickens,14-day-old chickens were randomly allocated into 3 groups.Group A was administrated with echinacea-astragalus mixture at a concentration of 1 mL,Group B and C with physiologic saline at the same time for succesive 7 days.The chickens in Group A and B were inoculated with infectious bursal disease virus(IBDV) at 21-day-old,then the dynamic distribution of CD4+,CD8+T lymphocytes in thymus and small intestine was detected by immunohistochemical examination.The results showed that,there exists differences in CD4+ lymphocyte of drug treated group and control group(P0.05),but no significance of CD8+ lymphocytes in both groups was obseved(P0.05).Compared with blank control group,CD4+ lymphocytes increased significantly(P0.05).At 24-day-old,CD4+ and CD8+T lymphocytes in thymus and small intestine also showed difference(P0.05).In the whole experimental stage,CD4+,CD8+T lymphocytes in thymus account for 60 percent of the examined thymus cells,and are more than those in small intestine.The result indicated that echinacea-astragalus mixture has a function of strengthening the immune function,as well as alleviating the pathological injury induced by IBDV notablely." @default.
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- W2349780842 date "2010-01-01" @default.
- W2349780842 modified "2023-10-02" @default.
- W2349780842 title "Effect of echinacea-astragalus on the dynamic distribution of CD4~+,CD8~+ T lymphocytes in thymus and small intestine of chickens infected with IBDV" @default.
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