Matches in SemOpenAlex for { <https://semopenalex.org/work/W2349781176> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2349781176 abstract "Objective To investigate the efficacy of Anluohuaxianwan and interferon α-1b combination therapy on liver fibrosis in patients with chronic hepatitis B(CHB).Methods Totally 129 CHB patients with liver fibrosis were randomly divided into 3 groups,including Anluohuaxianwan group(AL group)(40 cases),interferon α-1b(IFN group)(49 cases),and AL+IFN group(46 cases).The levels of serum fibrosis markers(PCⅢ,HA,CⅣ and LN) were detected through radioimmunoassay(RIA) at week 0,24 and 48 of treatment and week 24 after drug withdrawal.The symptoms,liver function,serological markers of HBV,HBV DNA titer and the imaging change under color Doppler were monitored,and pathologic change was also detected in 3 patients of each group undergoing biopsy.Results The total efficiency of AL group,IFN group and AL+IFN group were 70.0%,72.0% and 91.3%,respectively,at week 48 of treatment,and 75.0%,74.4% and 86.9%,respectively,at week 24 after withdrawal,and that of AL+IFN group was signi-ficantly higher than those of the other two groups(P0.05).The levels of PCⅢ,HA,CⅣ and LN in AL+IFN group decreased significantly after treatment(P0.05),and compared with AL group and IFN group,they decreased significantly after treatment and during follow-up(P0.05).At week 48 of treatment and week 24 after drug withdrawal,the negative seroconversion rates of HBeAg and HBV DNA in AL+IFN group were higher than those in AL group(P0.05),while no differences were found between AL+IFN group and IFN group.Conclusions The combination of Anluohuaxianwan and interferon α-1b has better effect on anti-fibrosis,anti-virus and improvement in liver function,which helps inhibit the progression of CHB." @default.
- W2349781176 created "2016-06-24" @default.
- W2349781176 creator A5055988301 @default.
- W2349781176 date "2011-01-01" @default.
- W2349781176 modified "2023-09-23" @default.
- W2349781176 title "Efficacy of Anluohuaxianwan and interferon α-1b combination therapy on liver fibrosis in patients with chronic hepatitis B" @default.
- W2349781176 hasPublicationYear "2011" @default.
- W2349781176 type Work @default.
- W2349781176 sameAs 2349781176 @default.
- W2349781176 citedByCount "0" @default.
- W2349781176 crossrefType "journal-article" @default.
- W2349781176 hasAuthorship W2349781176A5055988301 @default.
- W2349781176 hasConcept C126322002 @default.
- W2349781176 hasConcept C159654299 @default.
- W2349781176 hasConcept C176685330 @default.
- W2349781176 hasConcept C203014093 @default.
- W2349781176 hasConcept C2522874641 @default.
- W2349781176 hasConcept C2775934546 @default.
- W2349781176 hasConcept C2775940106 @default.
- W2349781176 hasConcept C2776178377 @default.
- W2349781176 hasConcept C2777382497 @default.
- W2349781176 hasConcept C2777410769 @default.
- W2349781176 hasConcept C2777451964 @default.
- W2349781176 hasConcept C2777766500 @default.
- W2349781176 hasConcept C2777785397 @default.
- W2349781176 hasConcept C2780559512 @default.
- W2349781176 hasConcept C2780593183 @default.
- W2349781176 hasConcept C2780678043 @default.
- W2349781176 hasConcept C2992208098 @default.
- W2349781176 hasConcept C32611913 @default.
- W2349781176 hasConcept C45189115 @default.
- W2349781176 hasConcept C71924100 @default.
- W2349781176 hasConcept C90924648 @default.
- W2349781176 hasConceptScore W2349781176C126322002 @default.
- W2349781176 hasConceptScore W2349781176C159654299 @default.
- W2349781176 hasConceptScore W2349781176C176685330 @default.
- W2349781176 hasConceptScore W2349781176C203014093 @default.
- W2349781176 hasConceptScore W2349781176C2522874641 @default.
- W2349781176 hasConceptScore W2349781176C2775934546 @default.
- W2349781176 hasConceptScore W2349781176C2775940106 @default.
- W2349781176 hasConceptScore W2349781176C2776178377 @default.
- W2349781176 hasConceptScore W2349781176C2777382497 @default.
- W2349781176 hasConceptScore W2349781176C2777410769 @default.
- W2349781176 hasConceptScore W2349781176C2777451964 @default.
- W2349781176 hasConceptScore W2349781176C2777766500 @default.
- W2349781176 hasConceptScore W2349781176C2777785397 @default.
- W2349781176 hasConceptScore W2349781176C2780559512 @default.
- W2349781176 hasConceptScore W2349781176C2780593183 @default.
- W2349781176 hasConceptScore W2349781176C2780678043 @default.
- W2349781176 hasConceptScore W2349781176C2992208098 @default.
- W2349781176 hasConceptScore W2349781176C32611913 @default.
- W2349781176 hasConceptScore W2349781176C45189115 @default.
- W2349781176 hasConceptScore W2349781176C71924100 @default.
- W2349781176 hasConceptScore W2349781176C90924648 @default.
- W2349781176 hasOpenAccess W2349781176 @default.
- W2349781176 hasRelatedWork W124965073 @default.
- W2349781176 hasRelatedWork W1586660353 @default.
- W2349781176 hasRelatedWork W1593529287 @default.
- W2349781176 hasRelatedWork W1972367502 @default.
- W2349781176 hasRelatedWork W198464306 @default.
- W2349781176 hasRelatedWork W2013118660 @default.
- W2349781176 hasRelatedWork W2047713508 @default.
- W2349781176 hasRelatedWork W2059114505 @default.
- W2349781176 hasRelatedWork W2080809802 @default.
- W2349781176 hasRelatedWork W2082236641 @default.
- W2349781176 hasRelatedWork W2367108460 @default.
- W2349781176 hasRelatedWork W2369475119 @default.
- W2349781176 hasRelatedWork W2372082589 @default.
- W2349781176 hasRelatedWork W2384552710 @default.
- W2349781176 hasRelatedWork W2387940564 @default.
- W2349781176 hasRelatedWork W2389195067 @default.
- W2349781176 hasRelatedWork W2404033525 @default.
- W2349781176 hasRelatedWork W2415023619 @default.
- W2349781176 hasRelatedWork W2419669715 @default.
- W2349781176 hasRelatedWork W3147299307 @default.
- W2349781176 isParatext "false" @default.
- W2349781176 isRetracted "false" @default.
- W2349781176 magId "2349781176" @default.
- W2349781176 workType "article" @default.