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- W2349843617 abstract "Aim:To investigate the changes of plasma adrenodullin(ADM)and c-type natriuretic peptide(CNP)level and the myocardial performance index(MPI)in children with chronic heart failure(CHF).Methods:A total of 42 children with CHF,including 12 cases of dilated cardiomyopathy,19 cases of congenital heart defects,and 11 cases of other heart diseases,were classified,and 16 cases as class Ⅱ,14 as class Ⅲ,and 12 as class Ⅳ.Plasma ADM and CNP levels were measured by radioimmunoassay,and MPI and LVEF were measured by echocardiography.Results:The plasma ADM and CNP levels of CHF patients before treatment were significantly higher than those of the control,and decreased after treatment(P0.05).The plasma ADM and CNP levels of CHF patients increased with the heart function degree(P0.05).There was no significant difference in the levels of ADM,CNP and MPI among different diseases(P0.05).The plasma CNP and ADM levels were significantly positively correlated to MPI(r were 0.87,0.59,respectively,P0.001),and negatively correlated to LVEF(r were-0.69,-0.48,respectively,P0.01)in the CHF patients.Conclusion:ADM may be a biochemical marker for evaluating the severity of the CHF in children." @default.
- W2349843617 created "2016-06-24" @default.
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- W2349843617 date "2007-01-01" @default.
- W2349843617 modified "2023-09-24" @default.
- W2349843617 title "Changes of plasma levels of adrenodullin,C-type natriuretic peptide and myocardial performance index in children with chronic heart failure" @default.
- W2349843617 hasPublicationYear "2007" @default.
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