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- W2349911345 abstract "AIM To study the value of detection of cancer associated antigens in serum and feces by using monoclonal antibodies against human col-orectal cancer.METHODS Cancer associated antigen in serum and feces was detected by using double - antibody sandwich ELISA method with human colonic cancer spectific monoclonal antibodes SC6 and SC3A. Forty -seven colorectal carcinomas, 33 colorectal adenomas, 15 hyperplastic polyps, 14 inflammatory polyps and 60 normal subjects were analysed. RESULTS The positivity rates of cancer associated antigen in serum and feces in colorectal cancers were 66.0% and 72.3% respectively, and in adenomas, 63.3% and 60.6%, hyperplastic polyps, 35.7% and 57. 1%, inflammatory polyps, 40. 0% and 33. 3%. But in normal group, the positivity rates were only 11.7% and 13.3%. The relation of Duke's stages of 45 carcinomas and the positivity rates of cancer associated antigen in serum and feces were further studied. The positivity rates for early colorectal cancers were 72.2% in feces and 50.0% in serum.CONCLUSION The detection of cancer associated antigens by ELISA method may be usefui for colorectal cancer diagnosis, and fecal detection may be more sensitive." @default.
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- W2349911345 date "1995-01-01" @default.
- W2349911345 modified "2023-09-23" @default.
- W2349911345 title "Study on detection of cancer associated antigen in serum and feces by monoclonal antibodies against hu-man colorectal cancer" @default.
- W2349911345 hasPublicationYear "1995" @default.
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