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- W2349932594 abstract "A crose over clinical pharmacokinetic study on latamoxef(shiomarin)was carried out in 8 normal male colunteers.1000 mg of latamoxef was fiven by iv or im injection.The concentrations of latamoxef in serum were detected by bioassay and HPLC mothods performed siumltaneously,The pharmacokinetic parameters were analyzed by 3P87 computer software.The serum concentration-time curve of the drug measured by two methods fitted two-compartment open model.The mean peak serum concentrations obtained after intravenous injection were 122.9-150.1 mg/l.The maximum serum concentration observed after intramuscuiar injection were 54.1-56. 8 mg/l at 1.11(-1).49 h.T_(1/2)βwere 2.74-3.37h.The results were in conformity w1lh the literatures.There were no significant difference between two detecting methods." @default.
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- W2349932594 date "1994-01-01" @default.
- W2349932594 modified "2023-09-25" @default.
- W2349932594 title "SINGLE DOSE PHARMACOKINETICS STUDY ON LATAMOXEF IN NORMAL VOLUNTEERS" @default.
- W2349932594 hasPublicationYear "1994" @default.
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