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- W2349947876 abstract "The glipizide- β -cyclodextrin ( β -CD) inclusion complex was prepared with n (glipizide)∶ n(β -CD)=1∶ 2 in time duration of 8 h,and inclusion rate of the inclusion complex was 91.73%.The results of HPLC showed that the main composition of glipizide had no change before and after being included by β -CD.The thermograph of DSC and X-ray powder diffraction pattern of the inclusion complex were remarkably different from those of glipizide and glipizide- β -CD mixture.The water-solubility of the inclusion complex was 10 times that of glipizide, and the dissolution rate of the inclusion complex was significantly increased. It was shown that the glipizide- β -CD inclusion complex exhibited some new physical characteristic and its physicochemical properties were significantly different from those of glipizide." @default.
- W2349947876 created "2016-06-24" @default.
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- W2349947876 date "2004-01-01" @default.
- W2349947876 modified "2023-09-23" @default.
- W2349947876 title "Preparation and Physicochemical Properties of Glipizide- β -Cyclodextrin Inclusion Complex" @default.
- W2349947876 hasPublicationYear "2004" @default.
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