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- W2349983658 abstract "AIM: To investigate the expression of transcription factor GATA-3 gene in the bone marrow stromal cells (BMSCs) from patients with aplastic anemia (AA) and normal controls. METHODS: The expression of GATA-3 gene was analyzed by using RT-PCR-ELISA in BMSCs from 34 normal cases and 9 cases with AA. The standardized semi-quantitative expression level of GATA-3 gene in BMSCs from patients with AA was compared with normal controls. RESULTS: The expression of GATA-3 gene was detected in BMSCs from both normal controls and the cases with AA. The expression level of GATA-3 gene in BMSCs from AA was significant higher than that from the normal controls (P0.05). CONCLUSION: The expression of GATA-3 gene was identified in BMSCs from normal controls and patients with AA. It may influence the function of immunity and the regulation of hematopoiesis in BMSCs. It may play the role in pathogenesis and development of AA." @default.
- W2349983658 created "2016-06-24" @default.
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- W2349983658 date "2006-01-01" @default.
- W2349983658 modified "2023-09-28" @default.
- W2349983658 title "Expression of transcription factor GATA-3 gene in bone marrow stromal cells from patients with aplastic anemia and normal controls" @default.
- W2349983658 hasPublicationYear "2006" @default.
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