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- W2350088510 abstract "Objective To review systematically the relationship between polymorphism of G894T in endothelial nitric oxide synthase ( eNOS ) gene and essential hypertension ( EH ) in Chinese Han population. Methods The original literature about the relationship between polymorphism of G894T in eNOS gene and EH were retrieved from China Journal Fulltext Database ( CJFD ) , China Scientific Journal Database ( CSJD ) , Chinese BioMedical Literature Database ( CBM ) , PubMed and Cochrane Library after establishing inclusion and exclusion criterions. All included literature were given Meta-analysis by using Rev Man 4.2 software. Results There were 13 studies included in Meta-analysis including 2593 cases with accumulated EH and 2620 health control cases. The included literature had higher heterogeneity. After combining analysis by using random effect model, the OR value of genotype frequency of effectsize ( GT+TT/GG ) was 1.39 ( 95% CI : 1.11-1.73, P 0.05 ) . The results of Meta-analysis was stable without significant bias after sensitivity analysis and publication bias assessment. Conclusion The polymorphism of G894T in eNOS gene is correlated to the susceptibility of EH in Chinese Han population." @default.
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- W2350088510 date "2012-01-01" @default.
- W2350088510 modified "2023-09-25" @default.
- W2350088510 title "A Meta-analysis on relationship between polymorphism of G894T in eNOS gene and essential hypertension in Chinese Han population" @default.
- W2350088510 hasPublicationYear "2012" @default.
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