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- W2350126051 abstract "Objective:To explore the efficacy and adverse drug effects of trazodone hydrochoride for the treatment of tramadol abusers with emotional disorders. Methods:Eighty two cases diagnosed with CCMD-3 criteria as tramadol abuse with emotional disorders were randomly divided into trial group(n=42)and control group (n=40). The two groups were treated, respectively with trazodone hydrochloride or clonazepam for 21 days. The largest doses of trazodone hydrochloride and clonazepam were ≤400 mg·d-1 and ≤4 mg·d-1, respectively. The efficacy was assessed with Hamilton Anxiety Scale(HAMA) and Hamilton Depression Scale (HAMD) and Global Assessment Scale (GAS), and the adverse drug effects were assessed with Treatment Emergent Symptoms Scale(TESS). Results:The effective rates of the trial group and control group were 88.1% and 42.5%, respectively, which showed significant difference between the two groups (P0.01). There was no remarkable difference in adverse effects between the two groups (P0.05). Conclusion:Trazodone hydrochloride is effective and safe in the treatment of tramadol abusers with emotional disorders." @default.
- W2350126051 created "2016-06-24" @default.
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- W2350126051 date "2008-01-01" @default.
- W2350126051 modified "2023-09-26" @default.
- W2350126051 title "EFFICACY OF TRAZODONE HYDROCHLORIDE FOR THE TREATMENT OF TRAMADOL ABUSERS WITH EMOTIONAL DISORDERS" @default.
- W2350126051 hasPublicationYear "2008" @default.
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