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- W2350149303 abstract "AIM and METHOD:Sexual difference of arrhythmia and the role of sexual hormone on arrhythmia were studied RESULTS:There was a sexual difference in arrhythmia evoked by aconitine in rats. The duration of arrhythmia was longer in female than male rats ( P 0.01), especially when female rats in oestrus. It was also proved that the difference was related to the estrogen level in rat blood. In estrogen-treated animals, the study shown that:① The duration of arrhythmia elicited by iv aconitine in male rats was shorten (68.6±18.2) min vs (47.1±19.6)min P 0.05;②The dosage of ouabin necessary to inducing VP and VF in male guinea pigs was increaseed (107.5±10.4) μg/kg vs (121.3±9.9) μg/kg, P 0.05;(151.3±14.6) μg/kg vs (167.5±11.7) μg/kg, P 0.05.③ The duration of arrhythmia evoked by adrenine under chloroform in male rabbits was reduced (262±54) s vs (145±22) s, P 0.01.CONCLUSION:There was a sexual difference in arrhythmia in rats and estrogen may have anti-arrhythmia effects in some male animals." @default.
- W2350149303 created "2016-06-24" @default.
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- W2350149303 date "1998-01-01" @default.
- W2350149303 modified "2023-09-23" @default.
- W2350149303 title "Association of arrythmia in experiment and sexual hormone" @default.
- W2350149303 hasPublicationYear "1998" @default.
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