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- W2350151621 abstract "Objective:To explore the relationship between lipoprotein-associated phospholipase A2(Lp-PLA2) and coronary heart disease(CHD) as well as type 2 diabetes mellitus(T2DM).Methods:Two hundred patients were enrolled in the study,and were subdivided into four groups.Factorial analysis of variance was used to study the relationships between Lp-PLA2and CHD as well as T2DM,and the relationships between C-reaction protein(CRP) and CHD as well as T2DM.And the correlation between the level of Lp-PLA2 and the severity of coronary atherosclerosis of patients with CHD and T2DM was calculated.Results:The levels of CRP of CHD group,T2DM group,and CHD+T2DM group were all higher than those of the control group(all P0.05).So was the level of Lp-PLA2(all P0.05).Factorial analysis of variance showed CHD and T2DM could interact with CRP and Lp-PLA2(F=7.62,P0.05;F=9.68,P0.05).The Gensini score of CHD+T2DM group was higher than that of CHD group(44.15±36.28 vs 60.51±42.58,P=0.020).The level of Lp-PLA2was positively correlated with the Gensini score in the CHD group(r=0.181,P=0.016).And so was the levels of Lp-PLA2 in the CHD+T2DM group(r=0.224,P=0.011).Conclusion:CHD and T2DM can interact with CRP and Lp-PLA2.Compared with the patients with coronary heart disease alone,the level of Lp-PLA2is higher and the coronary atherosclerosis is more severe for the patients with coronary heart disease and type 2 diabetes." @default.
- W2350151621 created "2016-06-24" @default.
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- W2350151621 date "2013-01-01" @default.
- W2350151621 modified "2023-10-14" @default.
- W2350151621 title "Relationship between lipoprotein-associated phospholipase A_2 and coronary heart disease as well as type 2 diabetes mellitus" @default.
- W2350151621 hasPublicationYear "2013" @default.
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