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- W2350201541 abstract "A series of new benzimidazole derivatives 1a-1g were synthesized from 3-nitrophthalic anhydride by ammonolysis,Hoffman degradation and reduction with hydrazine hydrate to give 2,3-diaminobenzoic acid,which was subjected to cyclization with aldehydes,chlorination with SOCl2,followed by amidation with amines. The test of their activity against Coxsackie virus B3 (CVB3) in Vero cells showed that compounds 1b,1c,1e and 1g had the better activity than that of ribavirin." @default.
- W2350201541 created "2016-06-24" @default.
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- W2350201541 date "2009-01-01" @default.
- W2350201541 modified "2023-09-25" @default.
- W2350201541 title "Synthesis of Novel Benzimidazole Derivatives and Their Antivirus Activity against Coxsackie Virus B_3" @default.
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