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- W2350202477 abstract "Objective: The purpose of this study was to identify the molecular basis of K + conductance in native bovine retinal pigment epithelium (RPE). Methods: RT-PCR, Northern blot were used to detect the expression of the inwardly rectifying K + (Kir) channel subunits Kir7.1 and Kir4.1 in native bovine RPE and neural retina. Results: RT-PCR analysis revealed Kir7.1 transcript in both RPE and neural retina, but Kir4.1 transcript in the neural retina alone. In Northern blots, Kir4.1 probe hybridized to an appropriately sized-transcript in neural retina but not in RPE. Kir7.1 probe hybridized to a major transcript of ～1.5 kb in both RPE and neural retina, but with greater expression in RPE. Conclusions:These results indicate that the Kir7.1 channel subunit, but not Kir4.1, is a major component of the K + conductance in bovine RPE." @default.
- W2350202477 created "2016-06-24" @default.
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- W2350202477 date "2004-01-01" @default.
- W2350202477 modified "2023-09-25" @default.
- W2350202477 title "Expression of Kir7.1 mRNA in native bovine retinal pigment epithelium" @default.
- W2350202477 hasPublicationYear "2004" @default.
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