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- W2350242705 abstract "OBJECTIVE To explore the antioxidaive effect of sulfydryl compound (Tiopronin) on pulmonary alveolar cell of rat with acute necrotic pancreatitis (ANP).METHODS The rats with ANP were divided randomly into three groups.Group A was treated with normal saline therapy, while group B was treated with Tiopronin. Group C was normal control group. SOD and MDA Level in pulmonary tissue were measured.The histopathological changes of pancreatic and lung tissue were observed.RESULTS The activity of SOD decreased markedly in group A and B, While MDA level increased significantly. The level of SOD in group B was higher than that of group A, While MDA level changed inversely. The histopathological changes appeared in group A and B. The injury of pulmonary alveolar cell and the quantity of ascites were decreased in group B, while compared with that of group A. The injury of the pulmonary alveolar cells under microscopy in group B was alleviated when compared with that of group A. CONCLUSIONS SOD level decreased markedly in rats with ANP, while MDA level increased markedly. Exgenous sulfydryl compound played an important role on the lung tissues of rats with ANP, probably as one of OFR scavengers." @default.
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- W2350242705 date "2005-01-01" @default.
- W2350242705 modified "2023-09-26" @default.
- W2350242705 title "Antioxidant effect of sulfydryl compound on lung of rat with acute necrotic pancreatitis" @default.
- W2350242705 hasPublicationYear "2005" @default.
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