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- W2350274587 abstract "Objective:To observe Qingnao Zhentong Liquid(QZL) through the mouth for 5 straight days,after filling in mice stomach give the analgesic action generated.Methods:120 SPF Kunming mice were randomly divided into the product high,medium and low dose group,positive and negative control group,each group 12 only,male and female half and half,the method of tenderness(n=60),acetic acid body torsion(n=60) according to improve rate of pain threshold,time of body torsion and body torsion times as the index.QZL was given according to 25 g liquid crude/kg or 12.5 g crude/kg weight through the mouth for 5 straight days to mice,the analgesic effect of Qingnao Zhentong Liquid was researched on mechanical stimuli and chemical stimulation the analgesic action which caused pain.Results:The product high dose group and positive control group could obviously improve the improve rate of pain threshold and compared with negative control group respectively,there were significant difference in them(P0.01),the improve rate of pain threshold in the product of low,medium dose group which compared with negative control group respectively,there was no significant difference.There were no significant differences on the first time of body torsion of the product of high,medium and low dose group and positive control group which compared respectively with negative control group.The body torsion times in the product of high,medium dose group were diminished,which were compared with negative control group and there were significant differences in them(P0.01).There were no significant differences on body torsion times of the product of low dose group compared with negative control group.Conclusion:QZL can observably increase the improve rat of pain threshold,and reduce the times of body torsion,so it has analgesic effect." @default.
- W2350274587 created "2016-06-24" @default.
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- W2350274587 date "2011-01-01" @default.
- W2350274587 modified "2023-09-23" @default.
- W2350274587 title "Empirical study on analgesic effect of Qingnao Zhentong Liquid" @default.
- W2350274587 hasPublicationYear "2011" @default.
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