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- W2350284221 abstract "Objective: To observe the ADRs and efficacy of 153Sm-EDTMP combined with MPA in treatment of bone pain in metastatic cancer patients. Methods: 32 patients were taken part in this study. They were treated with intravenous injection of 153Sm-EDTMP in a dose of 2.96×107-3.70×107Bq·kg-1 once each 4-6 weeks combined with MPA in a dose of 500mg·d-1. A therapeutic circle consisted of 14 consecutive days and 2 circles were needed. Results: The bone pain in 17 patients were completely relieved,9 patients were partially relieved and totally 26 patients were relieved.The effec-tive rate was up to 90% for bone pain in patients with prostate cancer and breast cancer. The quality of life in patients was signif icantly improved. The ADRs observed were mainly slight decrease in WBC and platelets.Conclusion:153Sm-EDTMP combined with MPA can be used as a therapeutic measure for treatment bone pain of metastatic multi-cancer with mild adverse drug reaction." @default.
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- W2350284221 date "2004-01-01" @default.
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- W2350284221 title "Treatment of 32 cases of bone pain of metastatic multi-cancer with (153)~Sm-EDTMP in combination with MPA" @default.
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