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- W2350312188 abstract "Objective: To compare efficacy and safety of Aripiprazole and Risperidone in the treatment of schizophrenia.Methods:60 patients with schizophrenia by CCMD-3 were randomly allocated to two groups treated with Aripiprazole or Risperidone for 8 weeks.The Positive.and Negative Syndrome Scale(PANSS)and Treatment Emergent Symptoms Scale(TESS) were used to evaluate efficacy and adverse effects respectively before treatment and at the end of 1,2,4 and 8 weeks.Results: The therapeutic efficacy in Aripiprazole group was similar to that in Risperidone(P0.05);There was no significant difference between the two groups(P0.05).Incidence of adverse effects in the Aripiprazole group was lower than that in the Risperidone group,but the difference was not significant(P0.05).The rates of extra-pyramidal symptoms and endocrine change were significantly higher in the Risperidone group than those in the Aripiprazole group.Conclusions: The results suggest that Aripiprazole is as effective as Risperidone for the treatment of schizophrenia and fewer side effects in them,although two drugs have different or the same side effects profile.,They both are efficacy and safety antipsychotic drugs in treatment of schizophrenia.They are beneficial to improve the therapeutic compliance of schizophrenic patients." @default.
- W2350312188 created "2016-06-24" @default.
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- W2350312188 date "2007-01-01" @default.
- W2350312188 modified "2023-09-23" @default.
- W2350312188 title "Comparison of efficacy and safety of Aripiprazole and Risperidone in the treatment of schizophrenia" @default.
- W2350312188 hasPublicationYear "2007" @default.
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