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- W2350321208 abstract "Objective:To access the values of glycosylated hemoglobin A1c(HBA1c)test in treating women with recurrent vulvovaginal candidiasis(RVVC).Methods:65 non-diabetes women with diagnosed RVVC were selected as subjects in the experimental group,and 60 candidia-negative patients,some of whom were healty without infections and the others contracted recurrent bacterial vaginosis(BV)were put in the control group.All patients were underwent fasting and 2 hours' post-prandial blood glucose test,and the body mass index were counted.58 RVVC patients whose HBA1c concentration ≥5% were randomly divided into 2 experimental groups:group I and group II.Patients in group I were treated with anti-fungus combined with glucose metabolism modfication,while patients in group II received the therapy with only anti-fungus.within 1 year after being cured,the relapse rate of all the subjects were statistically analyzed.Results:the proportion of patients with HBA1c≥5% in two experimental groups was significantly higher than that in the control group(89.23% vs 8.33%,P0.001).Women with RVVC had a significantly higher mean level in HBA1c,fasting glucose and body mass index than those in the control group,they were(5.49±0.41)% vs(4.36±0.66)%,(5.77±0.50)mmol/L vs(5.27±0.41)mmol/L and(22.87±4.47)kg/m2 vs(20.47±1.62)kg/m2 respectively,(P0.001).The 2 hours' post-prandial blood glucose level of the patients in the experimental group and the control group was(6.21±1.04)mmol/L and(5.86±0.95)mmol/L,and there was no obvious difference between the two groups(P0.05).The recurrence rate of those RVVC patients whose HBA1c was higher than or equal to 5% within 1 year after being cured in group I and group II was 6.90%(2/29)and 48.28%(14/29)respectively.There was significantly difference between the two experimental groups(P0.01).Conclusions:The plasma concentration of glycosylated HBA1c should be assayed,and HBA1c≥5% is suggested to be a critical point to limit sugar diet for patients,which will be of values to guide the clinical treatment in women with RVVC." @default.
- W2350321208 created "2016-06-24" @default.
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- W2350321208 date "2010-01-01" @default.
- W2350321208 modified "2023-09-22" @default.
- W2350321208 title "The sinificance of glycosylated hemoglobin A1c test in treating recurrent vulvovaginal candidiasis" @default.
- W2350321208 hasPublicationYear "2010" @default.
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