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- W2350360428 abstract "Objective: To study the relation between carotid artery atherosclerosis(AS) and the high level of plasma homocysteine(Hcy). Materials and Methods: Eighty-seven subjects with first-ever acute cerebral thrombosis in our department of neurology were enrolled from July 2002 to July 2003 as the patient group, with an average of (66.13±12.54)years old. Eighty subjects in the department of ophthalmology and department of otorhinolaryngology were selected as control group, with an average of (64.94±11.26)years old. High frequency ultrasonography was used to detect carotid artery intimal-medial wall thickness(IMT), the existence of atherosclerotic plaques and the stenosis of carotid arteries. Fast blood was collected to determine total plasma Hcy level, FBS, HbA1C, hepatic and renal function, TC, TG, LDL and HDL. Blood pressure, body height and weight were taken. Results: Fast plasma Hcy level was higher in the patient group[(15.28±4.33)μmolL] compared with that in control group[(11.32±3.86)μmolL](t=6.28, P0.001). In patient and control group, both differences in left and right carotid arteries IMT were statistically significant(t=3.647, P0.001; t=4.118, P0.001). The difference of incidence of carotid plaque was statistical significant(χ2=6.145, P=0.013). The risk factors were compared between the two groups. Logistic regression showed that plasma Hcy level, systolic pressure and BMI were the risk factors for cerebral thrombosis. There was no relationship between plasma Hcy level and either systolic pressure or BMI. Elevation in plasma Hcy level was an independent risk factor for acute cerebral thrombosis. Conclusion: Carotid artery AS correlate to high level of plasma Hcy." @default.
- W2350360428 created "2016-06-24" @default.
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- W2350360428 date "2004-01-01" @default.
- W2350360428 modified "2023-09-23" @default.
- W2350360428 title "Study on the relation between the ultrasonographic features of carotid artery atherosclerosisand the high level of plasma homocysteine" @default.
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