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- W2350378621 abstract "Objective To observe the response of endo -tracheal intubation under general anesthesia with the Shikani optical stylet induced by different dosage of fentanil and propofol or with endotracheal topical anesthesia through thyrocricoid puncture. Methods 60 patients with ASA Ⅰ～Ⅱ, aged from 20 to 65years, were divided into 3 groups (20 patients each). Besides midazolam 1～2mg, droperidol 1～2mg, and rocuronium 0.5mg/kg, the drugs for induction included fentanyl 2μg/kg and propofol 1.5mg/kg i.v. for group Ⅰ,fentanyl 3μg/kg and propofol 1.5mg/kg i.v. for group Ⅱ, as well as fentanyl 2μg/kg and propofol 1mg/kg i.v. for group Ⅲ. The endotracheal topical anesthesia was performed only in group Ⅲ with 2% dicaine 2ml through thyrocricoid puncture before rocuronium and propofol i.v. All the patients were monitored by the BIS, and intubation were performed with Shikani optical stylet when the BIS reached to the lowest. The BP, ECG, SPO2, PETCO2, BIS were continuously monitored and the cough reaction during extubation was scored. The bad memory events such as performances of intubation and thyrocricoid puncture were recorded 24h after operation. Results The BP, HR and BIS value dramatically dropped after induction in all patients. The BIS value in group Ⅱwas lower than that in group Ⅲ (P 0.05) . The BP, HR of patients in group ⅠandⅡ increased significantly after intubation, and were higher than that in group Ⅲ (P 0.05). The BP changes of group ⅠandⅡ were comparable, but the HR of group Ⅰwas faster than group Ⅱ (P 0.05). Cough during extubation happened in all three groups, but the score in group ⅠandⅡ were higher than that in group Ⅲ obviously (P 0.05). There was no uncomfortable memory in all three group patients. Conclusions With the sedation of midazolam and droperidol, fentanyl 2～3μg/kg and propofol 1.5mg/kg can inhibit the intubation response reasonably during tachy -induction endotracheal intubation with the Shikani optical stylet. If endotracheal topical anesthesia is performed, the propofol dosage can reduce to 1mg/kg and the intubation response can be much slighter." @default.
- W2350378621 created "2016-06-24" @default.
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- W2350378621 date "2009-01-01" @default.
- W2350378621 modified "2023-09-22" @default.
- W2350378621 title "Response of endo-tracheal intubation with Shikani optical stylet by different induction" @default.
- W2350378621 hasPublicationYear "2009" @default.
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