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- W2350394702 abstract "Objective To investigate the intravenous lipid emulsion of lomefloxacin aspartate and evaluate its stability. Methods After lecithin in glycerin and poloxamer were dissolved in purified water, heated by ultrasound machine then gently mixed with the oil phase at the same temperature, dispersed in tissue grinder before homogenized to the required standard. Its stability of the normal experiments was tested. Results Pharmacy properties of the lipid emulsion were studied, the average particle size was (162.50±9.32)nm; Zeta potential was (-30.67±1.93)mV and pH value was 7.32±0.02, all consistent with the intravenous standards of Pharmacopoeia 2010.Its stability was tested and verified by normal stability test and there was no significant change occurred. Conclusion The production process is simple and agent consumption is moderate and basically atoxic. The quality of the final product is stable. It could provide foundations for further animal experiments and clinic researches." @default.
- W2350394702 created "2016-06-24" @default.
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- W2350394702 date "2013-01-01" @default.
- W2350394702 modified "2023-09-25" @default.
- W2350394702 title "Preparation of intravenous lipid emulsion of lomefloxacin aspartate" @default.
- W2350394702 hasPublicationYear "2013" @default.
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