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- W2350402523 abstract "Objective To study the effects of various preparation methods on the properties of paclitaxel liposomes in vitro and choose the appropriate preparation method.Methods The paclitaxel liposomes were prepared by film dispersion method,ethanol injection method and pro-liposome method,respectively.The particle size distribution was determined by Malvern laser particle size analyzer and the encapsulation efficiency was detected by micro-column centrifugation-HPLC method.The formulation of liposomes was optimized by orthogonal design.Results The liposomes which were prepared by pro-liposome methods had uniform shape with proper particle size and higher encapsulation efficiency.Conclusion Preparation method has the remarkable influence on the properties of paclitaxel liposomes in vitro.Moreover,pro-liposome method was more suitable to prepare paclitaxel liposome and has unique advantages in the preparation of liposomes." @default.
- W2350402523 created "2016-06-24" @default.
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- W2350402523 date "2013-01-01" @default.
- W2350402523 modified "2023-09-23" @default.
- W2350402523 title "Effects of different preparation methods on the properties of paclitaxel liposomes in vitro" @default.
- W2350402523 hasPublicationYear "2013" @default.
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