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- W2350403046 abstract "Ion channels are transmembrane proteins that exist in virtually every cell type. They play essential roles in many physiological processes: maintenance of resting membrane potential, production and propagation of action potential, and regulation of neurotransmitter and hormone releases. Ion channels can be divided into two major categories based on the ions that permeate them: cationic and anionic. Examples of the former are potassium channels, calcium channels, and sodium channels. And chloride channels are good examples of the latter. According to their activation and gating mechanisms, ion channels can be further classified into many different types, such as voltage-dependent, Ca-activated, and ligand-gated. During the past two decades, the techniques that are used for studying ion channel activities have been greatly improved. The combination of electrophysiology and molecular biology has made it possible for the researchers to monitor the activities of ion channels at cellular and molecular levels. This little article will briefly introduce the technique of patch clamp and its application in the studies of ion channels in single smooth muscle cells." @default.
- W2350403046 created "2016-06-24" @default.
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- W2350403046 date "2002-01-01" @default.
- W2350403046 modified "2023-09-23" @default.
- W2350403046 title "Contemporary Electrophysilogical Techniques and Their Application in Physiology and Pharmacology" @default.
- W2350403046 hasPublicationYear "2002" @default.
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