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- W2350423559 abstract "Objective To prove the change of content of PGE2 in tissues of old colon carcinoma after operation.Methods The content of PGE2 in colon mucosa had been determined by radioimmunoassay. The old patients of colon carcinoma after operation had been divided into the treated group and the control group . The treated group patients(n=29) was administered with aspirin 0.3g, tid,for 12 months, the control group patients(n=28) was administered with Gushenchangan 0.8,tid,for 12 months. Results The PGE2 content in tissue of colon carcinoma (245.33±22.32pg/mg tissue)were higher than that in normal colon tissue(89.32±35.34 pg/mg tissue) , (P0.01) . The recurrence rate of colon carcinoma of elderly in aspirin treated group (10.3% ,20.7%)were lower than that in control group(25% ,43%) in 6 and 12 months after operation. Conclusions The PGE2 content in tissues of colon carcinoma of elderly was higher than that in normal colon tissue . Aspirin has likely some effects to prevent the recurrence of colon carcinoma of elderly after operation and inhibits the PGE2 synthesis in tissues of colon carcinoma of elderly." @default.
- W2350423559 created "2016-06-24" @default.
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- W2350423559 date "2004-01-01" @default.
- W2350423559 modified "2023-09-23" @default.
- W2350423559 title "The effect of aspirin on the content of PGE_2 in tissues colon carcinoma of elderly after operation" @default.
- W2350423559 hasPublicationYear "2004" @default.
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