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- W2350424054 abstract "Objective To elucidate the long time efficacy of thymic factor D(TFD),and to observe if it has a delayed effect.Method 742 patients with chronic hepatitis B were allocated to 2 groups:(1)Group A(n=572) received a 3 month course therapy with either a small dose of 10mg TFD intramuscular injection once a day or every other day,or a large dose of 50mg ivgtt once a day or every other day.(2)Group B(n=170) served as control without specific treatment.The two groups were comparable in clinicochemical features.Patients were followed up for 0.5～5 years.The complete virological response was defined as the loss of serum hepatitis B e antigen(HBeAg).The therapeutic effect was evaluated at the end of both treatment and follow up.Results The complete virological response rate was higher in group A(27.73%) than that in group B(9.86%) at the end of therapy( P 0.005).The complete response accumulated gradually during follow up.The complete response rate in group A was 43.02% whereas 13.90% in group B at the end of follow up( P 0.005).Conclusion There is a delayed effect of TFD therapy in the patients with chronic hepatitis B." @default.
- W2350424054 created "2016-06-24" @default.
- W2350424054 creator A5046523092 @default.
- W2350424054 date "2000-01-01" @default.
- W2350424054 modified "2023-09-25" @default.
- W2350424054 title "Prospective Study on Thymic Factor D Treating Patients with Chronic Hepatitis B" @default.
- W2350424054 hasPublicationYear "2000" @default.
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