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- W2350452864 abstract "OBJECTIVE To compare the expression of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 of nasopharyngeal carcinoma at Xi'an and Shenzhen area. METHOD The protein expression of MMP 9 and TIMP 1 were studied by immunohistochemistry staining in 21 cases nasopharyngeal carcinoma of Xi'an and 22 cases of Shenzhen. RESULT The expression positive rates of MMP-9 in nasopharyngeal carcinoma tissues at Xi'an and Shenzhen were 61.90% and 68.18%. The positive rates of TIMP-1 in nasopharyngeal carcinoma tissues at two regions were 28.57% and 31.82%. The expression between MMP-9 and TIMP-1 were negative relationship either Xi'an or Shenzhen. The expression of MMP-9 was positively correlated to lymph node metastasis, and TIMP-1 was no relationship with lymph node metastasis. The expression of MMP-9 and TIMP-1 was no difference between Xi'an and Shenzhen. CONCLUSION The expression of MMP-9 and TIMP-1 in nasopharyngeal carcinoma 2 tissues was no difference between Xi'an and Shenzhen. Increase of MMP-9 play an important role in progression and metastasis of nasopharyngeal carcinoma." @default.
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- W2350452864 date "2010-04-01" @default.
- W2350452864 modified "2023-09-24" @default.
- W2350452864 title "[Expression of MMP-9 and TIMP-1 in nasopharyngeal carcinoma and its signification at Xi'an and Shenzhen]." @default.
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