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- W2350473859 abstract "Objective To explore the biocompatibility of the nano-hydroxyapatite/collagen(NHAC),hydroxyapatite/collagen(HAC) and coralline-hydroxyapatite(CHA) with human bone marrow stem cell(BMSC) in order to offer the ideal bone material for treating bone defect.Methods The morphologic and fuction of the BMSC were observed by inverted phase contrast microscope,scanning electron microscope,MTT assay and the activity of alkaline phosphatase when coculturing three scaffolds with BMSC in vitro.Results The BMSC can adhere to proliferate and growth normally and perfectly on the surface and holes of NHAC and CHA.The cellular activity and alkaline phosphatase activity were not influenced by NHAC and CHA.HAC not only cannot benefit BMSC to adhere to and growth but also influence badly on the activity of alkaline phosphatase.Conclusion NHAC and CHA have good biocompatibility and can be used as an ideal biomaterial in bone tissue engineering.But HAC is not fit as a scaffold." @default.
- W2350473859 created "2016-06-24" @default.
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- W2350473859 date "2005-01-01" @default.
- W2350473859 modified "2023-09-27" @default.
- W2350473859 title "The comparative study on the biocompatibility of three scaffolds" @default.
- W2350473859 hasPublicationYear "2005" @default.
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