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- W2350509969 abstract "Aim To induce an experimental model in rats by E.coli tagged with GFP to investigate the significance of the invasion pathway of bacteria and the immune response in abacterial prostatitis and to establish a direct quantitative analysis method of pathogen.Methods After injecting 0.05 ml of of E.coli K88-GFP(1.49×109cfu·ml-1) liquid into the left dorsal lobe of SD rat prostate,a visualized method of bacterial prostatitis model was established through surface fluorescence image and tissue sections observed by fluorescence microscopy.Results ① The pathway of invasion and infection and the pathology changes of gland were confirmed.② A preliminary direct quantitative analysis method of pathogen was established.Conclusion Through constructing a visualized method of bacterial prostatitis model tagged with GFP,a direct quantitative analysis method of pathogen would be established and it provides a novel approach to further study of PK/PD for antibacterial." @default.
- W2350509969 created "2016-06-24" @default.
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- W2350509969 date "2013-01-01" @default.
- W2350509969 modified "2023-09-28" @default.
- W2350509969 title "GFP-based Escherichia coli in establishment of the visual model in rats of bacterial prostatitis" @default.
- W2350509969 hasPublicationYear "2013" @default.
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