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- W2350518114 abstract "The expression of p21 and p53 in rectal cancer and its relation to clinical pathological characteristics and the significance of its prognosis were studied.We examined the expression of p21 and p53 in paraffin embeded samples of 110 cases of rectal cancer using immunohistochemical method(SP method),the normal rectum of the same case was designed as control.The results showed that the positive rates of p21 and p53 were 54.5% and 42.7% respectively;The expression of p53 had no relation to clinical pathological characteristics and progrosis;the prognosis of the cases with negative expression of p21 was better;the expression of p21 had relations to histodifferentiation and lymphatic metastasis.It indicate that the occurance and development of rectal cancer are interrelated to the gene of p21 and p53;the prognosis of the cases with positive expression of p21 are worse;p21 may be regarded as the indication of judging the prognosis of rectal cancer." @default.
- W2350518114 created "2016-06-24" @default.
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- W2350518114 date "1999-01-01" @default.
- W2350518114 modified "2023-09-25" @default.
- W2350518114 title "Immunohistochemical studies on gene expression of p21 and p53 in rectal cancer" @default.
- W2350518114 hasPublicationYear "1999" @default.
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