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- W2350528103 abstract "Objective To explore the alterations of intestinal mucosa structure and permeability in chronic diarrhea.Methods 33 chronic diarrhea patients and 30 healthy volunteers were taken coloscopy,and got 3 pieces mucosa in terminal ileum and ileocecal junction each.The intestinal mucosa structure was detected by histopathological examination with light microscope.Gut barrier dysfunction was evaluated by detecting urine lactulose / mannitol(L/M) ratio.Results Endothelial cells in top of villi of terminal ileum were hydropsia,defluxion in chronic diarrhea patients,but there was not significant difference with healthy volunteers(P0.05);Covering epithelium cells in ileocecal junction obviously hydropsia,defluxion and defeated,even defluxion fully,there was significant difference with healthy volunteers(P0.05);And there was not significant difference in urine L/M ratio between chronic diarrhea and healthy volunteers(P0.05).Conclusion Chronic diarrhea maybe exist colon barrier dysfunction." @default.
- W2350528103 created "2016-06-24" @default.
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- W2350528103 date "2008-01-01" @default.
- W2350528103 modified "2023-09-23" @default.
- W2350528103 title "Study of intestinal mucosa structure and permeability in chronic diarrhea" @default.
- W2350528103 hasPublicationYear "2008" @default.
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