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- W2350553923 abstract "Objective To study the effect of Salvia miltiorrhiza on the renal injury in obstructive jaundice rats.Methods 64 cases of rats were randomly divided into four groups: the control group(CN),sham operated group(SO),obstructive jaundice group(OJ) and obstructive jaundice salvia miltiorrhiza treatment group(OJ+SM) ,16 cases in each.Plasma levels of endothelin-1(ET-1),total bililubin(TB),direct bililubin(DB),ures nitrogen(BUN) and creatinine(Cr) were measured on the 7th and 14th day after opreration.Renal histopathological changes were observed with light microscopy.Results In OJ group,the plasma levels of ET-1,TB,DB,BUN and Cr were higher than those in SO group(P0.01),the plasma levels of ET-1,TB,DB,Cr and BUN in OJ+SM group were lower than those in OJ group(P0.01),renal histopathological changes were improved.Conclusion Plasma ET-1 level increases in Wistar rats with obstructive jaundice,there is a positive correlationship between ET-1 and BUN and Cr,salvia miltiorrhiza may have the function of ameliorating renal disfunction by reducing ET-1 level." @default.
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- W2350553923 date "2006-01-01" @default.
- W2350553923 modified "2023-09-25" @default.
- W2350553923 title "The Experimental Study on the Effect of Salvia miltiorrhiza on the Renal Damages in Obstructive Jaundice Rats" @default.
- W2350553923 hasPublicationYear "2006" @default.
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