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- W2350566407 abstract "Objective:To evaluate the effects of disease duration and body weight on insulin secretion in type 2 diabetes.Methods:Type 2 diabetic patients were divided to groups according to the disease duration,and three insulin secretion indices(HOMA-β,INSR30,INSR120) of all groups were compared with the newly diagnosed group and the parameters in overweight / obese patients were compared with non-obese patients with same disease duration.Results:The insulin secretion ability decreased gradually as the disease duration extended.The statistical differences appeared when the disease duration exceeded 2 years.Insulin secretion was significantly higher in overweight / obese patients than that of non-obese one with the same disease duration.INSR30 and INSR120 increased 9.40% and 5.39% in overweight / obese patients with 2 to 4 years diabetes,respectively,when compared with newly onset group.Conclusion:Insulin secretion ability decreases with type 2 diabetes duration.There are differences of both insulin secretion ability and mode of change between overweigh / obese patients and non-obese one." @default.
- W2350566407 created "2016-06-24" @default.
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- W2350566407 date "2011-01-01" @default.
- W2350566407 modified "2023-09-23" @default.
- W2350566407 title "The effects of disease duration and body weight on insulin secretion ability in type 2 diabetes" @default.
- W2350566407 hasPublicationYear "2011" @default.
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