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- W2350644056 abstract "Objective To observe the effect of Zexie Decoction on compounding hypertension and hyperlipoidemia in rats.Methods Renal hypertension were fed high fat forage to set up the model of the rats of compounding renal hypertension and hyperlipoidemia.The rats of model were randomly divided into three groups:model group,Zexie Decoction group(2.19 g·kg-1),control group(18.75 g·kg-1 captopril+0.12 g·kg-1 Xuezhikang).The drugs were given by intragastric administration,once a day for 8 weeks.The systolic blood pressure(SBP),total cholesterol(TC),triglyceride(TG),low dansity lipoprotein-C(LDL-C) and high dansity lipoprotein-C(HDL-C) were measured.The pathology on the tissue slice of liver,kidney and thoracic aorta were observatied.Results SBP,TC,TG,LDL-C were significantly reduced(P0.05),HDL-C was significantly increased(P0.05),and the fatty liver,glomerular arteriosclerosis and thoracic aorta in membrane thickening symptoms were reduced after given Zexie Decoction.Conclusion Zexie Decoction has effect of depressurization and adjusting blood-fat,and has better protection for liver,kidney and thoracic aorta." @default.
- W2350644056 created "2016-06-24" @default.
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- W2350644056 date "2013-01-01" @default.
- W2350644056 modified "2023-09-23" @default.
- W2350644056 title "Experimental study on effect of Zexie Decoction on compounding hypertension and hyperlipoidemia rats" @default.
- W2350644056 hasPublicationYear "2013" @default.
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