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- W2350646802 abstract "Objective:To reveal the therapeutic mechanism of TCM compounds by studying the change of immunophenotype of bone marrow cells after medical intervention in lower-risk myelodysplastic syndrome(MDS) patients.Methods:Thirty qualified cases were randomly divide into treatment group(treated with Compound Shenlu Granules) and control group(treated with Andriol).The change of immunologic phenotype of bone marrow cells was observed before and after the treatment in the two groups.Results:MDS patients had higher expression of CD13,CD33,CD34,CD117 and HLA-DR,and lower expression of CD15 compared to normal control group(P 0.05).The expression level of HLA-DR remained unchanged before and after the treatment in both groups(P0.05).After treatment,the positive rates of CD33,CD34,CD13,CD117 were lower while the expression rate for CD15 was higher in the treatment group(P0.05 compared with those before treatment).In the control group,only expression rate for CD15 was increased after treatment(P0.05).Conclusion:The therapeutic mechanism of Compound Shenlu Granules for improving dyshaematopoiesis in MDS patients may be related to the function of promoting the maturation and proliferation of hematopoietic stem/progenitor cells." @default.
- W2350646802 created "2016-06-24" @default.
- W2350646802 creator A5037106996 @default.
- W2350646802 date "2013-01-01" @default.
- W2350646802 modified "2023-09-25" @default.
- W2350646802 title "Effect of Compound Shenlu Granules on Immunophenotype of Bone Marrow Cells in Lower-risk Myelodysplastic Syndrome Patients" @default.
- W2350646802 hasPublicationYear "2013" @default.
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