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- W2350652717 abstract "The benefits of antihypertensive therapy for the prevention of cardiovascular mortality and morbidity are well established.Meta analysis shows that antihypertensive therapy for the prevention of stroke and heart failure is 38% and 52% reduction,but only 16% for lowering coronary artery disease,which is much lower than 25%~48% reduction of epidemiology data antiparticipated,with the reduction of systolic blood pressure 10~12 mm Hg or diastolic blood pressure 5~6 mm Hg.Due to its multifactorial pathophysiology and its frequent association with other relevant risk factors and clinical conditions,treatment of hypertension requires an integrated approach,including lifestyle measures,antihypertensive drugs and other therapies.Yet,worldwide general practitioners continue to focus their attention on the management of a single risk factor,eg,blood pressure,rather than to global cardiovascular risk profile.Modern strategies of cardiovascular prevention in hypertensive patients should move from a single risk factor based approach toward a more comprehensive risk evaluation in the individual patient.The Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm(ASCOT-LLA) compared the effect of atorvastatin(10mg/d) with placebo in normolipidaemic hypertensive patients who had not experienced a coronary event but had at least three additional cardiovascular risk factors and were receiving concomitant blood pressure regulating therapy.The study was stopped early,after a median follow-up of 3.3 years,and convincingly demonstrated that low-density lipoprotein-lowering agents can decrease the risk of adverse ischemic events 36% in patients with hypertension." @default.
- W2350652717 created "2016-06-24" @default.
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- W2350652717 date "2011-01-01" @default.
- W2350652717 modified "2023-09-23" @default.
- W2350652717 title "Promoting Hypertension Treatment Strategy with Anti-Atherosclerosis" @default.
- W2350652717 hasPublicationYear "2011" @default.
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