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- W2350765866 abstract "Objective To investigate the effect of ischemic preconditioning on hepatic nitric oxide synthase in rat partial hepatectomy and its significance.Methods Twenty SD rats were randomly divided into 2 groups (n=0 in each group):Warm ischemie group (WI) and ischemic preconditioning group (IPC).Hepatic tissue (0.1g) was procured before warm ischemia and 0.5,1,2 and 3 h after reperfusion in WI group,before and after IPC and 0.5,1,2 and 3 h after reperfusion in IPC group.The expression of eNOS and iNOS mRNA was detected by fluorescence-quantitating-PCR.Results The expression of eNOS mRNA in liver was increased early after reperfusion in each group.It was stronger in IPC group than in WI group (P＜0.01 or P＜0.05).The expression of iNOS mRNA in liver was detected 1 h af- ter reperfusion.It was weaker in IPC group than in WI group (P＜0.05).Concluion In rat hepatecto- my,IPC may proctect liver from warm ischemia and reperfusion injury by promoting early hepatic expres- sion of eNOS mRNA after reperfusion and inhibitting later hepatic expression of iNOS mRNA after reperfusion." @default.
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- W2350765866 date "2006-01-01" @default.
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- W2350765866 title "Effect of ischemic preconditioning on hepatic nitric oxide synthase in rat partial hepatectomy and its significance" @default.
- W2350765866 hasPublicationYear "2006" @default.
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