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- W2350773856 abstract "Objective To investigate the anti-abortional effect of astragalus polysacharin (APS) on experimental aborting rats. Methods Sprague-Dawley(SD)rats injected with lipopolysaccharides (LPS) 1 μg per rat in tail vein on day 7 of pregnancy were used as aborting model,and the other injected with phosphate buffer solution ( PBS) 1. 0 mL per rat were used as normal group. The aborting rats were randomly divided into 3 groups: the control group,the abortion model group and the group treated with astragalus polysaccharin. The control group and abortion model group were given normal saline 2 mL from day 4 to day 9 of pregnancy via gastrogavage. The treated group was given astragalus polyaccharin 2 mL via gastrogavage during the same period. All the rats were killed on day 10 of pregnancy,and the abortion rates were assessed. Results A high miscarriage rate up to 8 /11 was observed in the LPS induced abortion group in contrast to 1 /12 in the control group. Conclusion LPS-induced abortion rate in rats can be decreased by treatment with astragalus polyaccharin." @default.
- W2350773856 created "2016-06-24" @default.
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- W2350773856 date "2010-01-01" @default.
- W2350773856 modified "2023-09-25" @default.
- W2350773856 title "Establishment of a LPS-Induced Rat Model of Abortion and the Effect of Astragalus Polysacharin on It" @default.
- W2350773856 hasPublicationYear "2010" @default.
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