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- W2350792888 abstract "Objective: To observe the effect and mechanism of Gubenzhike recipe on pulmonary function and sIgA level in respiratory tract of COPD mice.Methods: The mouse COPD model was established by exposure to cigarette smoke in combination with intra-nostrils injection of lipopolysaccharide.The mice were divided into three groups: negative control group,model group and Gubenzhike recipe group;Use the methods of HE eosin staining and electronic microscope to observe the morphology characteristic of COPD model;Test the pulmonary function by animal pulmonary function machine;Use the ELISA to test the sIgA level in respiratory tract.Results: The morphology characteristic is up to COPD;The FEV0.1,FEV0.2,FEF25-75,PEF and the content of sIgA in the upper respiratory tract in Gubenzhike recipe group had significant difference compared with those in model group(P0.05).The negative control group had no significant difference compared with Gubenzhike recipe group.Conclusion: Gubenzhike recipe might improve the pulmonary function and respiratory tract mucosa immunity of COPD model." @default.
- W2350792888 created "2016-06-24" @default.
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- W2350792888 date "2012-01-01" @default.
- W2350792888 modified "2023-09-26" @default.
- W2350792888 title "Effect of Gubenzhike recipe on pulmonary function and sIgA in respiratory tract of COPD mice" @default.
- W2350792888 hasPublicationYear "2012" @default.
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