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- W2350865475 abstract "Objective To study the best composition and dose ratio of polysaccharide-combination in vivo,and to explore the mechanism of its immunoenhancement.Methods This expremental was designed based on the L27(313) orthogonal.Four polysaccharides were selected as experimental factors and they were set to three doses from scratch.After polysaccharides combination intraperitoneal injection to the mice,the immune organ index,the spleen nature killer cell activity were studied.Results The best composition of polysaccharide-combinations on the immune activity was the composition of lichenan(8 mg/kg),ganoderan(16 mg/kg),astragalan(8 mg/kg) and lentinan(16 mg/kg).In the high,middle,low dosage levels,the index of spleen were 1.214±0.153,1.327±0.168,1.052±0.074,respectively.The index were all higher than the control group(0.554±0.069) significantly(P0.05 or P0.01).The index of thymus were 0.261±0.065,0.273±0.049,0.241±0.053,and were all higher than that of the control group(0.140±0.025) significantly(P0.05 or P0.01).Conclusion The ploysaccharide-combination with most apropriate doses ratio maybe provide the most effective way for pooducing the strongest immune-enhancing agent." @default.
- W2350865475 created "2016-06-24" @default.
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- W2350865475 date "2009-01-01" @default.
- W2350865475 modified "2023-09-27" @default.
- W2350865475 title "Effects of polysaccharide-combinations on immune activity of mice in vivo" @default.
- W2350865475 hasPublicationYear "2009" @default.
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