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- W2350934156 abstract "Seven quassinoids,three pregnanes and one ergostane-type sterol were isolated from the methanol extract of the seeds of Brucea javanica.Their structures were identified as yadanziolide A(1),bruteine D(2),yadanziosides A(3),C(4),F(5),G(6),L(7),3β-hydroxy-pregnan-5-en-20-one(8),3β-hydroxy-5α-pregnan-20-one(9),3-O-β-D-glucopyranosy-(1→2)-α-L-arabinopyranosyl-(20R)-pregn-5-ene-3β,20-diol(10),and(22E,24R)-5α,8α-epidioxy-ergosta-6,22-dien-3β-ol(11).Among them,compounds 8,9,and 11 were isolated from this plant for the first time.Additionally,the isolated quassinoids were evaluated for their cytotoxicity against a small panel of human cancer cell lines,and yadanziolide A(1) and bruteine D(2) were found to show significant cytotoxic activity." @default.
- W2350934156 created "2016-06-24" @default.
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- W2350934156 date "2013-01-01" @default.
- W2350934156 modified "2023-09-26" @default.
- W2350934156 title "Chemical Constituents from the Seeds of Brucea javanica and Their Cytotoxic Activities" @default.
- W2350934156 hasPublicationYear "2013" @default.
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